Randomized, Double Blind, Placebo Controlled Trial of Hydrosoluble Ubiquinol and Carnitine in Patients with Heart Failure: Longterm Follow up Results in the Tishcon Study
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چکیده
Background: Carnitine and coenzyme Q10 are important for myocardialmitochondrial function, and are deficient in patients with congestive heart failure. It is possible that supplementation with ubiquinol + lcarnitine may be protective among these patients, which may improve the quality of life and morbidity in heart failure. Subjects and Methods: In this controlled trial, the effects of carni Q-gel (L-carnitine fumarate 2250mg/day+hydrosoluble reduced ubiquinol 270mg/day) were examined for 15 months, in 31 (intervention group A) and another 31(control group B) patients with heart failure. Hospitalization due to worsening of heart failure, heart transplantation, and deaths were the
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تاریخ انتشار 2008